Upregulated Matrisomal Proteins and Extracellular Matrix Mechanosignaling Underlie Obesity-Associated Promotion of Pancreatic Ductal Adenocarcinoma

By sjmartinez • April 28, 2024

Waldron RT, Lugea A, Chang HH, Su HY, Quiros C, Lewis MS, Che M, Ramanujan VK, Rozengurt E, Eibl G, Pandol SJ. Upregulated Matrisomal Proteins and Extracellular Matrix Mechanosignaling Underlie Obesity-Associated Promotion of Pancreatic Ductal Adenocarcinoma. Cancers (Basel). 2024 Apr 21;16(8):1593. doi: 10.3390/cancers16081593. PMID: 38672675; PMCID: PMC11048773.

Tags: atypical flat lesions, Cedars Sinai DoM, Diet-induced obesity, Digestive Diseases, Extracellular matrix, KC mice, matrisomal proteins, pancreatic ductal adenocarcinoma, prognostic biomarkers, Publications, quantitative proteomic analysis, tandem mass tags, tumor microenvironment

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