A call for transparency, improved reporting, and interpretation of trials using surrogate end points in cardiac electrophysiology

By afschroeder • August 3, 2025

Tereshchenko LG, Manyara AM, Ciani O, Sodeke SO, Bradford CN, Santangeli P, Kapadia SR, Wazni O, Narayan SM, Chugh SS, Bilchick K, Huizar JF, Vaseghi M, Chung MK, Ellenbogen KA, Taylor RS. A call for transparency, improved reporting, and interpretation of trials using surrogate end points in cardiac electrophysiology. Heart Rhythm. 2025 Aug;22(8):e492-e499. doi: 10.1016/j.hrthm.2025.02.038. Epub 2025 Feb 26. PMID: 40021073; PMCID: PMC12317828.

Tags: Biomarker, Cardiology/Epi, Cedars Sinai DoM, Checklist, Clinical Trial, Outcome, Publications, Randomized Controlled Trial, Research design, standards, Surrogate end point, surrogate marker

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