Interaction between haploinsufficiency of PTPN2 and patient microbiome promotes autoimmune arthritis in mice

By afschroeder • August 3, 2025

Sendo S, Vela AJ, Ro M, Thiruppathy D, Wilkinson EL, Zhao Z, Hsieh WC, Yang S, Coras R, Bergot AS, Guma M, Nguyen A, McBride DA, Devkota S, Thomas R, Shah NJ, Svensson MND, Zengler K, Stanford SM, Bottini N. Interaction between haploinsufficiency of PTPN2 and patient microbiome promotes autoimmune arthritis in mice. J Autoimmun. 2025 Jul 31;156:103452. doi: 10.1016/j.jaut.2025.103452. Epub ahead of print. PMID: 40752380.

Tags: Cedars Sinai DoM, Digestive Diseases, Publications, Rheumatology

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