The ULK1-NCOA3 axis restrains de novo lipogenesis and prevents diet-induced steatohepatitis and fibrosis in mice

By afschroeder • April 3, 2026

Koo YD, Castillo RT, Sukumaran Nair A, Garneau M, Gochee C, Campbell ZV, Vakil TS, Ha J, Marti A, Soto J, Das D, Martinez-Lopez N, Sharma S, Delgado Y, Phung C, Ashley IA, Kapelczak ED, Jacobo R, Weatherford ET, Dai DF, Benhammou JN, Marshall AG, Hinton A Jr, Yang L, Pereira RO, TeSlaa T, Bouhaddou M, Singh R, Abel ED. The ULK1-NCOA3 axis restrains de novo lipogenesis and prevents diet-induced steatohepatitis and fibrosis in mice. J Clin Invest. 2026 Apr 2:e191101. doi: 10.1172/JCI191101. Epub ahead of print. PMID: 41926189.

Tags: Autophagy, cell biology, Digestive Diseases, Endocrinology, endocrinology, Hepatology, Obesity, Post Doc, Publications, Veterans Administration

The management of hepatorenal syndrome-acute kidney injury (HRS-AKI): A national survey of hepatology provider practices

Cullaro G, Im GY, Chandna S, Lee BT, Simonetto DA, Aby ES, Izzy M, Gonzalez SA, Sherman CB, Aron J, Luther J, Goel A, Jophlin[...]

Disparities in Healthcare Seeking and Physician Diagnosis of Irritable Bowel Syndrome: Results from a US Survey

Almario CV, Liu J, Higgins C, Yerneni N, Boules M, Chey WD, Chang L. Disparities in Healthcare Seeking and Physician Diagnosis of Irritable Bowel Syndrome:[...]

Gastric MALT Lymphoma in Plummer-Vinson Syndrome: Broadening the Spectrum of Associated Malignancies

Harmon R, Cheung N, Mendoza D, Fathizadeh P, Cole D, Chandna S. Gastric MALT Lymphoma in Plummer-Vinson Syndrome: Broadening the Spectrum of Associated Malignancies. ACG[...]