The ULK1-NCOA3 axis restrains de novo lipogenesis and prevents diet-induced steatohepatitis and fibrosis in mice

By afschroeder • April 3, 2026

Koo YD, Castillo RT, Sukumaran Nair A, Garneau M, Gochee C, Campbell ZV, Vakil TS, Ha J, Marti A, Soto J, Das D, Martinez-Lopez N, Sharma S, Delgado Y, Phung C, Ashley IA, Kapelczak ED, Jacobo R, Weatherford ET, Dai DF, Benhammou JN, Marshall AG, Hinton A Jr, Yang L, Pereira RO, TeSlaa T, Bouhaddou M, Singh R, Abel ED. The ULK1-NCOA3 axis restrains de novo lipogenesis and prevents diet-induced steatohepatitis and fibrosis in mice. J Clin Invest. 2026 Apr 2:e191101. doi: 10.1172/JCI191101. Epub ahead of print. PMID: 41926189.

Tags: Autophagy, cell biology, Digestive Diseases, Endocrinology, endocrinology, Hepatology, Obesity, Post Doc, Publications, Veterans Administration

Social and clinical determinants of liver transplant evaluation in hepatocellular carcinoma: A multicenter cohort study

Tincopa M, Bridi L, Vodkin I, Yilma M, Zhou K, Kwong A, Singh J, Mehta N, Kuo A, Hirose R, Wisel SA, Steggerda JA, Freise[...]

Irritable bowel syndrome and related disorders of gut-brain interaction

Black CJ, Chuah KH, Nasser Y, Remes-Troche JM, Shin A, Ford AC. Irritable bowel syndrome and related disorders of gut-brain interaction. Lancet. 2026 Oct 29:S0140-6736(26)01500-X.[...]

Conversational artificial intelligence for geriatric screening: A mixed-methods feasibility study

Naeim A, Cheng J, Spiegel B, Bakshian A, Tetrault E, Mehra M, Amini D, Krut Z, Shang H, Sedrak MS, Bui A, Johnson T, Wang[...]