Systems Genomics Reveals Age- and Sex-Dependent Metabolic Dysregulation from Glo1 Reduction in Mice

By afschroeder • January 17, 2026

Cely I, Blencowe M, Shu L, Diamante G, Ahn IS, Zhang G, LaGuardia J, Liu R, Briscoe O, Saleem Z, Wang S, Davis RC, Qi H, Lusis AJ, Yang X. Systems Genomics Reveals Age- and Sex-Dependent Metabolic Dysregulation from Glo1 Reduction in Mice. Physiol Genomics. 2026 Jan 16. doi: 10.1152/physiolgenomics.00106.2025. Epub ahead of print. PMID: 41543389.

Tags: Aging, Cardiology/Epi, Glyoxalase 1, Metabolic syndrome, Publications, sex differences, transcriptome

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