Description
We are organizing a Transplant Symposium on November 14 that will bring together leaders in the field to discuss cutting-edge advances in transplantation. Topics will include emerging biomarkers and diagnostics, novel therapies for antibody-mediated rejection and tolerance induction, and the latest developments in xenotransplantation. The program will also highlight innovative bioengineering and targeted therapeutic approaches that are shaping the future of transplant medicine
Register for the Symposium
email: NephrologyAdmin@mednet.ucla.edu
Agenda
8:00 – 9:20 AM Breakfast/Registration
Session I – Novel therapies for Antibody-Mediated Rejection (ABMR)
Moderators: Gabriel Danovitch / Supreet Sethi
9:20 – 9:30 AM Reza Abdi – Welcome & Opening
9:30 – 9:40 AM Kassem Safa “New Frontier in Desensitization: Two patients, Two therapies.”
9:40 – 10:05 PM Flavio Vincenti “Targeting Plasma cells and B cells with anti-CD3 iTEs (bi-specific T Cell Engagers) therapies for desensitization”
10:05 – 10:30 AM Sara Larson “Lessons from B Cell Directed Therapies in Cancer”
10:30 – 10:55 AM Stanley Jordan “Advances in Prevention & Treatment of Antibody-Mediated Rejection”
10:55 – 11:20 AM Georg Böhmig “Targeting antibody- and NK cell-driven kidney transplant rejection”
11:20 – 11:45 AM Jeff Veale “Delayed Immune Tolerance”
11:45 – 12:00 PM Panel discussion (15 min)
12:00 – 1:00 PM Lunch (1 hour)
Session II – Biomarkers for Kidney Transplant Rejection
Moderators: Julie Yabu / Basmah Abdalla
1:10 – 1:30 PM Philip Halloran “Molecular phenotyping of transplant rejection and injury”
1:30 – 1:50 PM Elaine Reed “The role of HLA and non-HLA antibodies in renal transplantation”
1:50 – 2:10 PM Neal Smith “New Pathology of Cardiac and Renal Antibody-Mediated Rejection”
2:10 – 2:30 PM Mike Bunnapradist “dd-CFDNA in Kidney Transplant”
2:30 – 2:40 PM Break (10 min)
Session III – Xenotransplantation and Tolerance
Moderators: Peter Heeger / Jerzy Kupiec
2:40 – 3:00 PM David Cooper/Shikhar Tripathi “Xenotransplantation: Lessons and Horizons”
3:00 – 3:20 PM Michael Curtis “Engineering Hope: Enabling the First Porcine Kidney Transplants in Humans”
3:20 – 3:40 PM Eckhard Wolf “Genetically modified Auckland Island organ source pigs”
3:40 – 4:00 PM Leonardo Riella “Clinical Kidney Xenotransplantation: The Massachusetts General Hospital Experience”
4:00 – 4:20 PM John David Cleveland (USC) “The True potential of Cardiac Xenotransplantation: Two-Year Survival in an Animal Model”
4:20 – 4:30 PM Panel Discussion (10 min)
Session IV – Engineering Innovations in Transplantation
Moderators: Andre Nel / Eric Lum
4:30 – 4:50 PM Reza Abdi “Precision Immune Therapy in Organ Transplantation”
4:50 – 5:10 PM Zhongwei Li “Kidney Engineering from Human Stem Cells.”
5:10 – 5:30 PM Abbas Ardehali “The next Chapter in Ex-vivo Heart and lung Perfusion”
5:30 – 5:50 PM Yangzhi Zhu “Real-Time Biosensing for Organ Transplantation: Assessing Graft Viability During Ex Situ Machine Perfusion”
5:50 – 5:55 PM Gabriel Danovitch – Closing Remarks (5 min)
Reception/Exhibitor Corner 6:00 pm to 7:30 pm
Meet the Speakers
Reza Abdi, MD
Professor of Medicine
Director of Kidney Transplant Immunobiology Program
UCLA David Geffen School of Medicine
Los Angeles, CA
Abbas Ardehali, MD, FACS
Professor of Surgery and Medicine at UCLA
Director of the Heart, Lung, and Heart-Lung Transplant Programs
David Geffen School of Medicine at UCLA
Los Angeles, CA
Georg A. Böhmig, MD
Professor of Medicine; Division of Nephrology and Dialysis,
Medical University of Vienna
Vienna, Austria
Suphamai (Michael) Bunnapradist, MD, MS
Professor of Clinical Medicine
David Geffen School of Medicine at UCLA
Los Angeles, CA
John D. Cleveland, MD
Associate Professor of Clinical Surgery
Program Director, Congenital Cardiac Surgery Fellowship
Associate Chief, Division of Cardiothoracic Surgery
Children’s Hospital Los Angeles
Los Angeles, CA
David K.C. Cooper, MD, PhD, FRCS
Adjunct Professor of Surgery, Thomas E. Starzl
Transplantation Institute, University of Pittsburgh Medical Center
Pittsburgh, PA
Mike Curtis, PhD
President & Chief Executive Officer at eGenesis
Philip F. Halloran, MD, PhD OC
Director, Alberta Transplant Applied Genomics Centre
Professor of Medicine, University of Alberta,
Edmonton, Alberta, Canada
Stanley Jordan, MD
Professor of Medicine and Pediatrics at
Cedars-Sinai Medical Center
Director of Nephrology, the Kidney Transplant Program, and the
HLA and Transplant Immunology Laboratory
Los Angeles, CA
Sara Larson, MD
Assistant Professor of Medicine, hematologist-oncologist
UCLA David Geffen School of Medicine
Los Angeles, CA
Zhongwei Li, PhD
Associate Professor, Medicine, Stem Cell Biology and
Regenerative Medicine
Elaine F. Reed, PhD
Professor of Pathology and Laboratory Medicine
Director of the UCLA Immunogenetics Center
David Geffen School of Medicine at UCLA
Los Angeles, CA
Leonardo V. Riella, MD, PhD
Medical Director, Kidney Transplant Program,
Massachusetts General Hospital
Associate Professor of Medicine, Harvard Medical School
Boston, MA
Kassem Safa, MD
Associate Professor
Medical Director, UCLA Kidney Transplant Program
UCLA David Geffen School of Medicine
Los Angeles, CA
Neal Smith, MD, PhD
Associate Professor
Clinical and Laboratory Pathology, Anatomic Pathology
Mass General Brigham
Boston, MA
Shikhar Tripathi, MD
Professor, Department of Hematology
Transplantation Institute
Pittsburgh, PA
Jeffrey L. Veale, MD
Professor of Urology at UCLA
Director of the UCLA Kidney Transplant Exchange Program
David Geffen School of Medicine at UCLA
Los Angeles, CA
Flavio G. Vincenti, MD
Clinical Professor of Medicine and Surgery
Endowed Chair in Kidney Transplantation
UCSF
San Francisco, CA
Eckhart Wolf, PhD
Professor
Chair of Molecular Animal Breeding and Biotechnology
Gene Center and Department of Veterinary Sciences
Ludwig-Maximilians-Universität München
Munich, Germany
Yangzhi Zhu, PhD
Director, Biomedical Device Center
Associate Professor and Core Faculty,
Terasaki Institute for Biomedical Innovation
Los Angeles, CA