DGAT1-associated lipid-retinoid dysregulation correlates with metabolic impairment in the RPE of Stargardt disease

By afschroeder • July 29, 2026

Dave A, Ng ESY, Jiang Z, Hu J, Tatang J, Paniagua A, Doeve J, Parikh S, Williams KJ, Stiles L, Radu RA. DGAT1-associated lipid-retinoid dysregulation correlates with metabolic impairment in the RPE of Stargardt disease. iScience. 2026 Jul 13;29(8):116727. doi: 10.1016/j.isci.2026.116727. PMID: 42519008; PMCID: PMC13382123.

Tags: ABCA4, ATP-binding cassette transporter protein, Endocrinology, lipidomics, macular degeneration, mitochondrial dysfunction, Publications, retinal pigment epithelium, retinoids, Stargardt disease

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