Osteopontin stabilization and collagen containment slows amorphous calcium phosphate transformation during human aortic valve leaflet calcification

By sjmartinez • May 29, 2024

Sivaguru M, Mori S, Fouke KW, Ajijola OA, Shivkumar K, Samuel AZ, Bhargava R, Fouke BW. Osteopontin stabilization and collagen containment slows amorphous calcium phosphate transformation during human aortic valve leaflet calcification. Sci Rep. 2024 May 28;14(1):12222. doi: 10.1038/s41598-024-62962-8. PMID: 38806601; PMCID: PMC11133482.

Tags: ACP, Amorphous calcium phosphate, aortic valve, Cardiology/Epi, Cardiovascular calcification, Cholesterol, Coalescing spherules, Collagen alteration, Collagen containment, GeoBioMed, HAP, Hydroxyapatite, lipids, Nodules, osteopontin, Publications, Spherules, Super-resolution autofluorescence

Advancements in Artificial Intelligence for Enhanced Diagnosis and Prognosis in Cardiac CT: a Comprehensive Review and Future Perspectives

Adabifirouzjaei F, Budoff M, Nomeli M. Advancements in Artificial Intelligence for Enhanced Diagnosis and Prognosis in Cardiac CT: a Comprehensive Review and Future Perspectives. Curr[...]

Patient Communication and Radiation Safety in [177Lu]Lu-PSMA Radiopharmaceutical Therapy: International Survey of 102 Theranostic Centers

Zahner J, Unterrainer LM, Czernin J, Calais J, Eiber M, Fendler WP, Werner RA, Gardner L, Allen-Auerbach M, Benz MR. Patient Communication and Radiation Safety[...]

Metabolic Niches: MALDI Imaging Reveals Lipidomic Heterogeneity in the Human Heart

Osumi KM, Kransdorf EP, Manzoor D, Karlstaedt A, Neumann EK. Metabolic Niches: MALDI Imaging Reveals Lipidomic Heterogeneity in the Human Heart. J Am Soc Mass[...]