A Phase 1b, Randomized, Double-Blind, Placebo-Controlled, Multiple-Ascending Dose Study to Investigate the Safety, Tolerability, and Pharmacokinetics of DSTA4637S in Patients With Complicated Staphylococcus aureus Bacteremia Receiving Standard-of-Care Antibiotics

By afschroeder • October 9, 2026

Miller LG, Fowler VG, Miro JM, Horcajada JP, Lewin-Koh N, Chu T, Rymut S, Gutierrez J, Rosenberger CM, Hazenbos WLW, Glickstein S, Couch JA, Peck MC. A Phase 1b, Randomized, Double-Blind, Placebo-Controlled, Multiple-Ascending Dose Study to Investigate the Safety, Tolerability, and Pharmacokinetics of DSTA4637S in Patients With Complicated Staphylococcus aureus Bacteremia Receiving Standard-of-Care Antibiotics ^†. Open Forum Infect Dis. 2026 Sep 26;13(10):ofag608. doi: 10.1093/ofid/ofag608. PMID: 42846794; PMCID: PMC13643602.

Tags: antibody–antibiotic conjugate, bacteremia, Clinical Trial, Harbor UCLA, Infectious Diseases, Publications, Staphylococcus aureus

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