Regulatory T cell modulation with selective CD28 blockade and IL-6 receptor antagonist in kidney transplant recipients: results of CTOT-24, a prospective clinical trial

By afschroeder • July 23, 2026

Chandran S, Tang Q, Leung JC, Armstrong BD, Friedewald JJ, Kirk AD, Laszik ZG, Goldstein J, Morsheimer M, Vincenti FG. Regulatory T cell modulation with selective CD28 blockade and IL-6 receptor antagonist in kidney transplant recipients: results of CTOT-24, a prospective clinical trial. Am J Transplant. 2026 Jul 22:S1600-6135(26)02676-6. doi: 10.1016/j.ajt.2026.07.016. Epub ahead of print. PMID: 42486389.

Tags: belatacept, Cedars Sinai DoM, Clinical Trial, costimulation blockade, Interleukin-6, kidney transplantation, lulizumab, Nephrology, Publications, regulatory T cells, Tocilizumab

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