Metabolic and Glycemic Effects of Orforglipron, a GLP-1 Receptor Agonist, in Adults With or Without Diabetes: A Network Meta-Analysis of Randomised Clinical Trials

By afschroeder • July 23, 2026

Hageen AW, Gadelmawla AF, Saleh AO, Mohamed MR, Abdallfatah A, Elsekhary A, El-Nemr AF, Eladawi S, Maihoub O, Abdulhay H, Turkmani M, Abdelazeem B, Fonarow GC. Metabolic and Glycemic Effects of Orforglipron, a GLP-1 Receptor Agonist, in Adults With or Without Diabetes: A Network Meta-Analysis of Randomised Clinical Trials. Endocrinol Diabetes Metab. 2026 Jul;9(4):e70275. doi: 10.1002/edm2.70275. PMID: 42487237.

Tags: body weight, Cardiology/Epi, glucagon‐like peptide‐1 receptor agonists, HbA1c, Obesity, orforglipron, Publications

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