A Porcine Model of Intervertebral Disc Injury Recapitulates Human Discogenic Pain Via Notochordal Cell Loss and Pain-Inducing Nucleus Pulposus Cell Emergence

By afschroeder • July 10, 2026

Kaneda G, Wechsler JT, Chavez M, Sheyn J, Cheema K, Shen C, Rigo De Righi D, Wang L, Hsu YC, Avalos P, Xie Y, Tawackoli W, Floyd C, Li D, Sheyn D. A Porcine Model of Intervertebral Disc Injury Recapitulates Human Discogenic Pain Via Notochordal Cell Loss and Pain-Inducing Nucleus Pulposus Cell Emergence. JOR Spine. 2026 Jul 9;9(3):e70200. doi: 10.1002/jsp2.70200. PMID: 42428568; PMCID: PMC13347629.

Tags: biobehavioral tests, biomedical sciences, Cedars Sinai DoM, discogenic pain, General Internal Medicine, intervertebral disc degeneration, Low Back Pain, notochordal cells, nucleus pulposus, porcine model, Publications

Integrating Natural Language Processing With ChatGPT to Improve Quality of Artificial Intelligence Summaries of Prostate Cancer Consultations

Friedrich NA, Das SK, Luu M, Daniels JP, Heard J, Barsegyan A, Freedland SJ, Spiegel B, Kokorowski PK, Gonzalez Hernandez G, Daskivich TJ. Integrating Natural[...]

Clinical Triage of Individuals With Warning Symptoms of Imminent Cardiac Arrest

Reinier K, Chugh H, Kadiyala V, Sargsyan A, Uy-Evanado A, Nakamura K, Heckard E, Mathias M, Grogan T, Elashoff D, Salvucci A, Jui J, Chugh[...]

Comparing incidence of heart failure in individuals with enlarged cardiac chambers versus diabetes

Mirjalili SR, Atlas K, Reeves AP, Zhang C, Wasserthal J, Azimi A, Hashemi A, Mozafarybazargany M, Ghaffari Jolfayi A, Atlas T, Henschke CI, Yankelevitz DF,[...]