IBS stress reactivity phenotype is associated with blood transcriptome profiles and microstructural and functional brain changes

By afschroeder • May 12, 2026

Labus JS, Delgadillo DR, Cole S, Wang C, Joshi S, Church A, Naliboff B, Chang L, Jacobs JP, Ellingson BM, Mayer EA. IBS stress reactivity phenotype is associated with blood transcriptome profiles and microstructural and functional brain changes. Neurobiol Stress. 2026 Apr 8;42:100806. doi: 10.1016/j.ynstr.2026.100806. PMID: 42110977; PMCID: PMC13156650.

Tags: CREB transcription, Diffusion tensor imaging, Digestive Diseases, Functional brain connectivity, Irritable Bowel Syndrome, Proinflammatory genes, Publications, stress reactivity, Veterans Administration

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