Whole Genome Sequence Analysis of Weight Loss in 16 972 Participants With COPD Reveals Novel Risk Loci in DRAIC and RFX3

By afschroeder • April 24, 2026

Chiles JW 3rd, Rocco A, Srinivasasainagendra V, Rossiter HB, Casaburi R, Thalacker-Mercer A, Wells JM, Wan ES, Silverman EK, Cho MH, Hersh CP, Psaty BM, Gharib SA, Gao Y, O'Connor GT, Lange LA, Rich SS, Manichaikul AW, Barr RG, Ortega VE, Meyers DA, Smith AV, Tiwari HK, McDonald MN. Whole Genome Sequence Analysis of Weight Loss in 16 972 Participants With COPD Reveals Novel Risk Loci in DRAIC and RFX3. J Cachexia Sarcopenia Muscle. 2026 Jun;17(3):e70293. doi: 10.1002/jcsm.70293. PMID: 42026014.

Tags: Cachexia, COPD, Genomics, Harbor UCLA, Publications, Pulmonary, Critical Care & Sleep Medicine, wasting, weight loss

A practical approach to Cardiopulmonary Exercise Testing: from functional evaluation to adapted exercise prescription

Neunhaeuserer D, Gevaert AB, Hansen D, Battista F, Bauer P, Davos CH, Ermolao A, Sanz-de la Garza M, Guazzi M, Howden EJ, Laukkanen J, Mueller-Stegner[...]

Impact of metastatic pattern and histologic subtype on PD-(L)1 inhibitor efficacy in HER2-negative advanced gastric and gastroesophageal cancer: a meta-analysis

Tai D, Kim KI, Shah P, Park D, Kim L, Li J, Jung C, Guzman S, Brar G, Wu S, Castillo D. Impact of metastatic[...]

Investigating the Kidney-Gut-Brain Axis in CKD: Uremic Toxins and Brain Microhemorrhages

Zhao Y, Lee SM, Li W, Floriolli D, Chang P, Narasaki Y, You AS, Kalantar-Zadeh K, Rhee CM, Liu H, Tran T, Paganini-Hill A, Fisher[...]