Whole Genome Sequence Analysis of Weight Loss in 16 972 Participants With COPD Reveals Novel Risk Loci in DRAIC and RFX3

By afschroeder • April 24, 2026

Chiles JW 3rd, Rocco A, Srinivasasainagendra V, Rossiter HB, Casaburi R, Thalacker-Mercer A, Wells JM, Wan ES, Silverman EK, Cho MH, Hersh CP, Psaty BM, Gharib SA, Gao Y, O'Connor GT, Lange LA, Rich SS, Manichaikul AW, Barr RG, Ortega VE, Meyers DA, Smith AV, Tiwari HK, McDonald MN. Whole Genome Sequence Analysis of Weight Loss in 16 972 Participants With COPD Reveals Novel Risk Loci in DRAIC and RFX3. J Cachexia Sarcopenia Muscle. 2026 Jun;17(3):e70293. doi: 10.1002/jcsm.70293. PMID: 42026014.

Tags: Cachexia, COPD, Genomics, Harbor UCLA, Publications, Pulmonary, Critical Care & Sleep Medicine, wasting, weight loss

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