Feasibility and Implementation of INTERVAL-GAP4: A Global Randomised Controlled Trial of Intense Hybrid-supervised/Self-managed Versus Self-directed Exercise for Metastatic Prostate Cancer

By afschroeder • January 22, 2026

Kenfield SA, Hart NH, Courneya KS, Greenwood R, Chan JM, Sison J, Zhang L, Rudman S, Ung L, Schumann M, Van Blarigan EL, McKeown S, Ryan CJ, Catto J, Galvão DA, Newton RU, Saad F; INTERVAL-GAP4 Site Investigators and INTERVAL-GAP4 Steering and Management Committees. Feasibility and Implementation of INTERVAL-GAP4: A Global Randomised Controlled Trial of Intense Hybrid-supervised/Self-managed Versus Self-directed Exercise for Metastatic Prostate Cancer. Eur Urol Open Sci. 2026 Jan 7;84:29-39. doi: 10.1016/j.euros.2025.12.001. PMID: 41561488; PMCID: PMC12814685.

Tags: Cancer, Castrate resistant, Cedars Sinai DoM, exercise, General Internal Medicine, Hormone sensitive, intervention, Metastasis, Physical Medicine & Rehabilitation, Publications, survival

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Geft D, Matusov Y, Kolaitis N, DesJardin J, Barnett C, Hage A, De Marco T, Lewis MI. Response. Chest. 2026 Feb;169(2):e80-e81. doi: 10.1016/j.chest.2025.11.028. PMID: 41672669.

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