UTX coordinates TCF1 and STAT3 to control progenitor CD8+ T cell fate in autoimmune diabetes

By afschroeder • December 17, 2025

Chen HC, Bang MF, Wang HH, Shpargel KB, Kohn LA, Sailer D, Zhang S, McCarthy EC, Seyedsadr M, Stevens S, Pham CLH, Zhou Z, Yin X, Wilkinson NM, Peluso EM, Bustillos C, Ortega JG, Yang L, Buzzelli AA, Capati RC, Chia DJ, Mittelman SD, Reh CM, Whitmire JK, Lechner MG, Hugo W, Su MA. UTX coordinates TCF1 and STAT3 to control progenitor CD8+ T cell fate in autoimmune diabetes. J Clin Invest. 2025 Dec 16:e196325. doi: 10.1172/JCI196325. Epub ahead of print. PMID: 41401033.

Tags: Allergy & Immunology, Autoimmune Diseases, autoimmunity, Dermatology, diabetes, Endocrinology, epigenetics, Immunology, Publications

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