Akebia Saponin D Targeting Ubiquitin Carboxyl-Terminal Hydrolase 4 Promotes Peroxisome Proliferator-Activated Receptor Gamma Deubiquitination and Activation of Brown Adipose Tissue Thermogenesis in Obesity

By afschroeder • October 17, 2025

Chen L, Liu DH, Li YX, Yang S, Jia WH, Peng L, Liu HL, Wang XB, Hu B, Wang YC, Pan C, Lusis AJ, Liu LH, Gong LL. Akebia Saponin D Targeting Ubiquitin Carboxyl-Terminal Hydrolase 4 Promotes Peroxisome Proliferator-Activated Receptor Gamma Deubiquitination and Activation of Brown Adipose Tissue Thermogenesis in Obesity. MedComm (2020). 2025 Oct 15;6(11):e70420. doi: 10.1002/mco2.70420. PMID: 41104164; PMCID: PMC12521790.

Tags: Akebia Saponin D, Cardiology/Epi, deubiquitination, mitochondria, Obesity, Publications, ubiquitin carboxyl‐terminal hydrolase 4

Population Modeling Approach for Human Cardiac Arrhythmia Risk Prediction

Song Z, Sui F, Huang X, Liu MB, Gao W, Weiss JN, Qu Z. Population Modeling Approach for Human Cardiac Arrhythmia Risk Prediction. Circ Arrhythm[...]

Race and Ethnic-Specific Burden of Aortic Valve Calcium and Its Association With Long-Term Aortic Stenosis: Multi-Ethnic Study of Atherosclerosis

Grant JK, Jha K, Marrero N, Razavi AC, Boakye E, Anchouche K, Dzaye O, Budoff MJ, Shah S, Czarny MJ, Rotter JI, Guo X, Yao[...]

Amara Yad Image: Sectional View of the Left Ventricular Outflow Tract Viewed From the Superior Direction

Goel NE, Shivkumar K. Amara Yad Image: Sectional View of the Left Ventricular Outflow Tract Viewed From the Superior Direction. J Am Coll Cardiol. 2026[...]