Overcoming ovarian cancer resistance and evasion to CAR-T cell therapy by harnessing allogeneic CAR-NKT cells

By afschroeder • August 14, 2025

Li YR, Li Z, Zhu Y, Li M, Chen Y, Lee D, Ochoa CJ, Singh T, DiBernardo G, Guo W, Li S, Zhou Y, Yu Y, Kramer A, Wilson M, Zhou K, Dunn ZS, Fang Y, Yu J, Kim YJ, Huang J, Shen X, Wang YC, Hon R, Basso T, Chen E, Zhu E, Lin S, Neal A, Moatamed NA, Oh SS, Sadeghi S, Pan C, Wang A, Lusis AJ, Zhou XJ, Zhou JJ, Pellegrini M, Wang P, Memarzadeh S, Yang L. Overcoming ovarian cancer resistance and evasion to CAR-T cell therapy by harnessing allogeneic CAR-NKT cells. Med. 2025 Aug 5:100804. doi: 10.1016/j.medj.2025.100804. Epub ahead of print. PMID: 40803321.

Tags: allogeneic CAR-NKT cells, allorejection, cancer immunotherapy, Cardiology/Epi, cytokine release syndrome, Dermatology, graft-versus-host disease, Hematology/Oncology, hematopoietic stem and progenitor cells, invariant natural killer T cells, ovarian cancer, Pre-clinical research, Publications, tumor immune resistance and evasion, tumor microenvironment, Veterans Administration

Efficacy and safety of bridging intravenous thrombolysis before mechanical thrombectomy: A systematic review and meta-analysis

Hashmi TM, Ahmed M, Ashraf H, Shakir M, Bhatti IA, Alareed A, Ahmed F, Hasan A, Ahmed R, Aized MT, Rafiq S, Fonarow GC, Hassan[...]

Not Premature to Quantitatively Define the Near-Field Bipolar Electrogram for Premature Ventricular Contraction Ablation

Ji S, Gupta N, Qu Z. Not Premature to Quantitatively Define the Near-Field Bipolar Electrogram for Premature Ventricular Contraction Ablation. J Arrhythm. 2025 Sep 1;41(5):e70183.[...]

Racial and Ethnic Differences in Patient Age at First Hospitalization for Heart Failure

Huang X, Hughes Z, Fonarow GC, Ahmad FS, Shah NS, Chuzi S, Kershaw KN, Greenland P, Khan SS, Petito LC. Racial and Ethnic Differences in[...]