Overcoming ovarian cancer resistance and evasion to CAR-T cell therapy by harnessing allogeneic CAR-NKT cells

By afschroeder • August 14, 2025

Li YR, Li Z, Zhu Y, Li M, Chen Y, Lee D, Ochoa CJ, Singh T, DiBernardo G, Guo W, Li S, Zhou Y, Yu Y, Kramer A, Wilson M, Zhou K, Dunn ZS, Fang Y, Yu J, Kim YJ, Huang J, Shen X, Wang YC, Hon R, Basso T, Chen E, Zhu E, Lin S, Neal A, Moatamed NA, Oh SS, Sadeghi S, Pan C, Wang A, Lusis AJ, Zhou XJ, Zhou JJ, Pellegrini M, Wang P, Memarzadeh S, Yang L. Overcoming ovarian cancer resistance and evasion to CAR-T cell therapy by harnessing allogeneic CAR-NKT cells. Med. 2025 Aug 5:100804. doi: 10.1016/j.medj.2025.100804. Epub ahead of print. PMID: 40803321.

Tags: allogeneic CAR-NKT cells, allorejection, cancer immunotherapy, Cardiology/Epi, cytokine release syndrome, Dermatology, graft-versus-host disease, Hematology/Oncology, hematopoietic stem and progenitor cells, invariant natural killer T cells, ovarian cancer, Pre-clinical research, Publications, tumor immune resistance and evasion, tumor microenvironment, Veterans Administration

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