The protein deacetylase SIRT2 exerts metabolic control over adaptive Beta cell proliferation

By afschroeder • August 6, 2025

Wortham M, Ramms B, Zeng C, Benthuysen JR, Sai S, Pollow DP, Liu F, Schlichting M, Harrington AR, Liu B, Prakash TP, Pirie EC, Zhu H, Baghdasarian S, Lee ST, Ruthig VA, Wells KL, Auwerx J, Shirihai OS, Sander M. The protein deacetylase SIRT2 exerts metabolic control over adaptive β cell proliferation. J Clin Invest. 2025 Jul 31:e187020. doi: 10.1172/JCI187020. Epub ahead of print. PMID: 40762838.

Tags: beta cells, diabetes, Endocrinology, endocrinology, Metabolism, mitochondria, Publications

Safety and Efficacy of Repeat Surgery for Recurrent Craniopharyngiomas: A RAPID Consortium Collaboration

Shih RM, Harary M, Bergsneider M, Wang M, Heaney AP, Wu KC, Prevedello DM, Evans JJ, Chicoine MR, Kim AH, Silverstein JM, Karsy M, Van[...]

Longitudinal Outcomes in Immune Checkpoint Inhibitor-Associated Uveitis

Yun JS, Feo A, Chew L, Feng J, Hutchins E, Stein-Merlob AF, Yang EH, Lechner MG, Tsui E. Longitudinal Outcomes in Immune Checkpoint Inhibitor-Associated Uveitis.[...]

Development of insulin resistance in women over the menopause transition

Karlamangla AS, Han WJ, Srikanthan P, Shieh A, Thomas D, Sternfeld B, Hedderson MM, Greendale GA. Development of insulin resistance in women over the menopause[...]