Macrophage-derived Spp1 promotes intramuscular fat in dystrophic muscle

By afschroeder • July 9, 2025

Farahat PK, Kumagai-Cresse C, Aragón RL, Ma F, Amakor JK, Espinoza A, Kramerova I, Jimenez RJ, Smith BM, Perez J, Crosbie RH, Nagendra AH, McCourt-Towner J, Coulis G, Ikotun OF, Pyle AD, Pellegrini M, McNally EM, Villalta SA, Spencer MJ. Macrophage-derived Spp1 promotes intramuscular fat in dystrophic muscle. JCI Insight. 2025 Jul 8;10(13):e181946. doi: 10.1172/jci.insight.181946. PMID: 40626359.

Tags: Dermatology, genetics, Monogenic diseases, Muscle, Muscle biology, Publications

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