Integrated hepatic transcriptomics and metabolomics identify Pck1 as a key factor in the broad dysregulation induced by vehicle pollutants

By sjmartinez • December 30, 2024

Ramanathan G, Zhao Y, Gupta R, Langmo S, Bhetraratana M, Yin F, Driscoll W, Ricks J, Louie A, Stewart JA, Gould TR, Larson TV, Kaufman J, Rosenfeld ME, Yang X, Araujo JA. Integrated hepatic transcriptomics and metabolomics identify Pck1 as a key factor in the broad dysregulation induced by vehicle pollutants. Part Fibre Toxicol. 2024 Dec 30;21(1):55. doi: 10.1186/s12989-024-00605-6. PMID: 39734207.

Tags: Air pollution, Cardiology/Epi, Diesel exhaust, gluconeogenesis, Glycogenolysis, Liver, metabolomics, mitochondrial dysfunction, Pck1, Publications, Transcriptomics

SARS-CoV-2 nucleocapsid induces hyperinflammation and vascular leakage through the Toll-like receptor signaling axis in macrophages

Yao Z, Alvarez PA, Chavez C, Delgado Y, Kaushal P, Buchholz DW, Austin D, Li Q, Yu Y, Zaiss AK, Arumugaswami V, Ding Q, Hsu[...]

Isochronal Versus Electrogram-Based Conduction Velocity Estimation to Predict Inducible Monomorphic Ventricular Tachycardia in Repaired Tetralogy of Fallot

O'Leary ET, Waldmann V, Bessière F, Tan RB, Mariucci E, Chang PM, Kanter RJ, Cohen MI, Khairy P, Moore JP. Isochronal Versus Electrogram-Based Conduction Velocity[...]

Ambient fine particulate matter components and liver fat and stiffness in youth: metabolic vulnerability in PNPLA3 risk carriers

Li H, Schenker RB, Marquess KM, Paudel D, Ramirez CB, Lurmann F, Ren M, Jang C, Allayee H, Liao J, Chen Z, Goran MI, Alderete[...]