Integrated hepatic transcriptomics and metabolomics identify Pck1 as a key factor in the broad dysregulation induced by vehicle pollutants

By sjmartinez • December 30, 2024

Ramanathan G, Zhao Y, Gupta R, Langmo S, Bhetraratana M, Yin F, Driscoll W, Ricks J, Louie A, Stewart JA, Gould TR, Larson TV, Kaufman J, Rosenfeld ME, Yang X, Araujo JA. Integrated hepatic transcriptomics and metabolomics identify Pck1 as a key factor in the broad dysregulation induced by vehicle pollutants. Part Fibre Toxicol. 2024 Dec 30;21(1):55. doi: 10.1186/s12989-024-00605-6. PMID: 39734207.

Tags: Air pollution, Cardiology/Epi, Diesel exhaust, gluconeogenesis, Glycogenolysis, Liver, metabolomics, mitochondrial dysfunction, Pck1, Publications, Transcriptomics

Related Posts

Immunomodulatory Microneedle Patch for Cardiac Repair in Rodent and Porcine Models of Myocardial Infarction

Huang K, Zhu D, Soto J, Hu S, Fang J, Huang J, Zhang X, Li J, Li Y, Tasoudis P, Liu S, Mei X, Hoffman[...]

One-year outcomes of the RESILIA balloon-expandable transcatheter valve: survival, hemodynamics, and hypoattenuated leaflet thickening

Suruga K, Patel V, Guo Y, Shitan H, Ng D, Nagasaka T, Menda J, Singh A, Gheorghiu M, Patel D, Gupta A, Chakravarty T, Cheng[...]

Optimization of Image Quality for Quantitative Multi-Contrast Atherosclerosis Characterization (qMATCH): Comparison Between Transverse and Coronal Acquisitions

Hsu YC, Lu M, Llanes A, Keushkerian MJ, Nguyen KL, Johnson K, Altbach MI, Morris HD, DeMarco JK, Deshpande V, Mitsouras D, Saloner D, McNally[...]