ZIP8 A391T Crohn’s Disease-Linked Risk Variant Induces Colonic Metal Ion Dyshomeostasis, Microbiome Compositional Shifts, and Inflammation

By sjmartinez • September 26, 2024

Yang JC, Zhao M, Chernikova D, Arias-Jayo N, Zhou Y, Situ J, Gutta A, Chang C, Liang F, Lagishetty V, Jacobs JP. ZIP8 A391T Crohn's Disease-Linked Risk Variant Induces Colonic Metal Ion Dyshomeostasis, Microbiome Compositional Shifts, and Inflammation. Dig Dis Sci. 2024 Sep 25. doi: 10.1007/s10620-024-08647-8. Epub ahead of print. PMID: 39322808.

Tags: Crohn’s disease, DGSOM Student, Digestive Diseases, Gene-environment, microbiome, Mucosal-luminal interface, Post Doc, Publications, Trace metals

Increased mortality from alcohol use disorder, alcohol-associated liver disease, and liver cancer from alcohol among older adults in the United States: 2000 to 2021

Danpanichkul P, Duangsonk K, Tham EKJ, Tothanarungroj P, Auttapracha T, Prasitsumrit V, Sim B, Tung D, Barba R, Wong RJ, Leggio L, Yang JD, Chen[...]

Biogeographical distribution of gut microbiome composition and function is partially recapitulated by fecal transplantation into germ-free mice

Yang JC, Lagishetty V, Aja E, Arias-Jayo N, Chang C, Hauer M, Katzka W, Zhou Y, Sedighian F, Koletic C, Liang F, Dong TS, Situ[...]

Extended flexible sigmoidoscopy using water exchange facilitates a complete colon examination without sedation in participants undergoing average risk colorectal cancer screening: results from a randomized trial

Bak A, Parker B, Perini R, Aulakh A, Oliveira C, Richardson W, Hirschkorn P, Sullivan B, Recsky M, Orlando T, Leung F. Extended flexible sigmoidoscopy[...]