Dysregulation of cholesterol homeostasis is an early signal of beta cell proteotoxicity characteristic of type 2 diabetes

By sjmartinez • July 2, 2024

Gurlo T, Liu R, Wang Z, Hoang J, Ryazantsev S, Daval M, Butler AE, Yang X, Blencowe M, Butler PC. Dysregulation of cholesterol homeostasis is an early signal of beta cell proteotoxicity characteristic of type 2 diabetes. Physiol Genomics. 2024 Jul 1. doi: 10.1152/physiolgenomics.00029.2024. Epub ahead of print. PMID: 38949617.

Tags: beta cell, Cholesterol, Endocrinology, IAPP, islet amyloid polypeptide, Publications, RNA-seq, Type 2 diabetes

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