Ceramide synthesis mediates colorectal cancer metastasis through a YAP-driven regenerative program

By afschroeder • September 25, 2026

Goswami S, Zhang Q, Yildiz AB, Das Adhikari U, Raghawan AK, Bulliard M, Sedhain S, Darawshi O, Celik CE, Cansiz F, Krempe CP, Rösler J, Allies G, Meckelmann SW, Chi C, Hormann FL, Heiles S, Sedlak J, Grace W, Eng G, Reich E, Alquati C, Williams KJ, Read BJ, Rashan EH, Li Z, Jnawali A, Ortiz JA, Jain C, Whittaker CA, Yilmaz OH, Deshpande V, Schmitz OJ, Sickmann A, York AG, Kwon DS, Neumann U, Fedorova M, Vander Heiden MG, Ogretmen B, Sethi NS, Tasdogan A, Yilmaz ÖH. Ceramide synthesis mediates colorectal cancer metastasis through a YAP-driven regenerative program. Science. 2026 Sep 24;393(6818):eadw8520. doi: 10.1126/science.adw8520. Epub 2026 Sep 24. PMID: 42784694.

Tags: Endocrinology, Publications

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