Osteopontin stabilization and collagen containment slows amorphous calcium phosphate transformation during human aortic valve leaflet calcification

By sjmartinez • May 29, 2024

Sivaguru M, Mori S, Fouke KW, Ajijola OA, Shivkumar K, Samuel AZ, Bhargava R, Fouke BW. Osteopontin stabilization and collagen containment slows amorphous calcium phosphate transformation during human aortic valve leaflet calcification. Sci Rep. 2024 May 28;14(1):12222. doi: 10.1038/s41598-024-62962-8. PMID: 38806601; PMCID: PMC11133482.

Tags: ACP, Amorphous calcium phosphate, aortic valve, Cardiology/Epi, Cardiovascular calcification, Cholesterol, Coalescing spherules, Collagen alteration, Collagen containment, GeoBioMed, HAP, Hydroxyapatite, lipids, Nodules, osteopontin, Publications, Spherules, Super-resolution autofluorescence

Sodium-Glucose Cotransporter 2 Inhibitor Use and Outcomes in Transthyretin Amyloid Cardiomyopathy

Jaiswal V, Hanif M, Mashkoor Y, Jaiswal A, Prasad T, Rajak K, Khan MS, Mentz RJ, Fonarow GC. Sodium-Glucose Cotransporter 2 Inhibitor Use and Outcomes[...]

Genetic Variants Associated with the Biochemical Response to Vitamin D3 in the Multi-Ethnic Study of Atherosclerosis

Best CM, Li X, Rotter JI, Prince DK, Hsu S, Hoofnagle AN, Siscovick D, Taylor KD, Williams K, Michos ED, Psaty BM, Shea S, Rice[...]

Initiation and sequencing of guideline-directed medical therapy for heart failure across the ejection fraction spectrum

Shahid I, Khan MS, Butler J, Fonarow GC, Greene SJ. Initiation and sequencing of guideline-directed medical therapy for heart failure across the ejection fraction spectrum.[...]