Single-cell sequencing reveals Hippo signaling as a driver of fibrosis in hidradenitis suppurativa

By sjmartinez • February 2, 2024

van Straalen KR, Ma F, Tsou PS, Plazyo O, Gharaee-Kermani M, Calbet M, Xing X, Sarkar MK, Uppala R, Harms PW, Wasikowski R, Nahlawi L, Nakamura M, Eshaq M, Wang C, Dobry C, Kozlow JH, Cherry-Bukowiec J, Brodie WD, Wolk K, Uluçkan Ö, Mattichak MN, Pellegrini M, Modlin RL, Maverakis E, Sabat R, Kahlenberg JM, Billi AC, Tsoi LC, Gudjonsson JE. Single-cell sequencing reveals Hippo signaling as a driver of fibrosis in hidradenitis suppurativa. J Clin Invest. 2024 Feb 1;134(3):e169225. doi: 10.1172/JCI169225. PMID: 38051587.

Tags: Cytokines, Dermatology, dermatology, fibrosis, Inflammation, Publications, skin

Assessing GPT-4’s Diagnostic Accuracy with Darker Skin Tones: Underperformance and Implications

Akuffo-Addo E, Samman L, Munawar L, Akbik M, Kokikian N, Wescott R, Wu JJ. Assessing GPT-4's Diagnostic Accuracy with Darker Skin Tones: Underperformance and Implications.[...]

Engaging industry effectively and ethically in artificial intelligence from the Augmented Artificial Intelligence Committee Standards Workgroup

Lee I, Aninos A, Lester J, Rotemberg V, Schlessinger DI, Weed J, Wongvibulsin S, Daneshjou R. Engaging industry effectively and ethically in artificial intelligence from[...]

A phase 1 study of triple-targeted therapy with BRAF, MEK, and AKT inhibitors for patients with BRAF-mutated cancers

Algazi AP, Moon J, Lao CD, Chmielowski B, Kendra KL, Lewis KD, Gonzalez R, Kim K, Godwin JE, Curti BD, Latkovic-Taber M, Lomeli SH, Gufford[...]