GMP-grade human neural progenitors delivered subretinally protect vision in rat model of retinal degeneration and survive in minipigs

By sjmartinez • September 25, 2023

Lu B, Avalos P, Svendsen S, Zhang C, Nocito L, Jones MK, Pieplow C, Saylor J, Ghiam S, Block A, Fernandez M, Ljubimov AV, Small K, Liao D, Svendsen CN, Wang S. GMP-grade human neural progenitors delivered subretinally protect vision in rat model of retinal degeneration and survive in minipigs. J Transl Med. 2023 Sep 25;21(1):650. doi: 10.1186/s12967-023-04501-z. PMID: 37743503.

Tags: animal models, Cedars Sinai DoM, Endocrinology, Good manufacturing practice, Publications, Retinal degeneration, Retinitis pigmentosa, Stem/neural progenitor cells, Toxicology study

cGAS-STING dependent type I IFN reduces Leptospira interrogans renal colonization in mice

Gupta S, Matsunaga J, Ratitong B, Manion A, Ismaeel S, Valadares DG, West AP, Kerur N, Stehlik C, Dorfleutner A, Dagvadorj J, Coburn J, Wolf[...]

Design and Rationale of the WARRIOR Ancillary Study for Coronary CT Angiographic Analysis

Tamarappoo B, Wolny R, Tomasino GF, Berman D, Handberg E, Pepine CJ, Lo MC, Budoff M, Shaw L, Shufelt C, Wei J, Gulati M, Merz[...]

Public Health

Tan ZS, Qureshi N, Sicotte N, Escovedo C, Hirsch A, Afrashteh A, Miles PB, Roberts P. Public Health. Alzheimers Dement. 2025 Dec;21 Suppl 6(Suppl 6):e101651.[...]