Single-cell Profiling of Prurigo Nodularis Demonstrates Immune-Stromal Crosstalk Driving Profibrotic Responses and Reversal with Nemolizumab

By sjmartinez • July 29, 2023

Ma F, Gharaee-Kermani M, Tsoi LC, Plazyo O, Chaskar P, Harms P, Patrick MT, Xing X, Hile G, Piketty C, Lazzari A, Van Delm W, Maverakis E, Nakamura M, Modlin RL, Kahlenberg JM, Billi AC, Julia V, Krishnaswamy JK, Gudjonsson JE. Single-cell Profiling of Prurigo Nodularis Demonstrates Immune-Stromal Crosstalk Driving Profibrotic Responses and Reversal with Nemolizumab. J Allergy Clin Immunol. 2023 Jul 26:S0091-6749(23)00925-9. doi: 10.1016/j.jaci.2023.07.005. Epub ahead of print. PMID: 37506977.

Tags: Dermatology, fibrosis, Inflammation, nemolizumab, Prurigo nodularis, Publications, single-cell RNA-sequencing, spatial-sequencing

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