Apabetalone Downregulates Fibrotic, Inflammatory and Calcific Processes in Renal Mesangial Cells and Patients with Renal Impairment

By sjmartinez • June 28, 2023

Gilham D, Wasiak S, Rakai BD, Fu L, Tsujikawa LM, Sarsons CD, Carestia A, Lebioda K, Johansson JO, Sweeney M, Kalantar-Zadeh K, Kulikowski E. Apabetalone Downregulates Fibrotic, Inflammatory and Calcific Processes in Renal Mesangial Cells and Patients with Renal Impairment. Biomedicines. 2023 Jun 8;11(6):1663. doi: 10.3390/biomedicines11061663. PMID: 37371758.

Tags: apabetalone, BET proteins, chronic kidney disease (CKD), epigenetics, fibrosis, gene expression, Harbor UCLA, Inflammation, Nephrology, Publications

Aortic valve calcium as a novel risk marker for kidney function deterioration: The MESA study

Abdollahi A, Sani MM, Shabani M, Matuck BS, Blaha MJ, Wu CO, Ambale-Venkatesh B, Budoff MJ, Strom JB, Rotter JI, Post WS, Blumenthal RS, Bluemke[...]

Methotrexate associates with ischemic cardiovascular risk reduction in males but not females: a transatlantic cardiovascular consortium for people with rheumatoid arthritis observational study

Karpouzas GA, Ormseth SR, Van Riel P, Myasoedova E, Gonzalez-Gay MA, Corrales A, Rantapaa-Dahlqvist S, Sfikakis P, Dessein P, Hitchon CA, Pascual-Ramos V, Yanez IC,[...]

Bouveret syndrome in 2 parts: endoscopic removal of residual cholelithiasis with closure of cholecystoduodenal fistula after initial surgical management

Cumpian NA, Atla PR, Alao H, Eysselein V, Reicher S. Bouveret syndrome in 2 parts: endoscopic removal of residual cholelithiasis with closure of cholecystoduodenal fistula[...]