Apabetalone Downregulates Fibrotic, Inflammatory and Calcific Processes in Renal Mesangial Cells and Patients with Renal Impairment

By sjmartinez • June 28, 2023

Gilham D, Wasiak S, Rakai BD, Fu L, Tsujikawa LM, Sarsons CD, Carestia A, Lebioda K, Johansson JO, Sweeney M, Kalantar-Zadeh K, Kulikowski E. Apabetalone Downregulates Fibrotic, Inflammatory and Calcific Processes in Renal Mesangial Cells and Patients with Renal Impairment. Biomedicines. 2023 Jun 8;11(6):1663. doi: 10.3390/biomedicines11061663. PMID: 37371758.

Tags: apabetalone, BET proteins, chronic kidney disease (CKD), epigenetics, fibrosis, gene expression, Harbor UCLA, Inflammation, Nephrology, Publications

Efficacy assessments of SF001, a next-generation polyene antifungal, in a neutropenic mouse model of invasive fusariosis

Gebremariam T, Gu Y, Patterson H, Youssef E, Alkhazraji S, Elsayed T, Wiederhold NP, Ibrahim AS. Efficacy assessments of SF001, a next-generation polyene antifungal, in[...]

CD19 Expression in B-Cell Lymphomas and Clinical Considerations in the Evolving Landscape of CD19-Targeted Therapy

Marshalek JP, Qing X, Tomassetti S. CD19 Expression in B-Cell Lymphomas and Clinical Considerations in the Evolving Landscape of CD19-Targeted Therapy. World J Oncol. 2025[...]

Racial differences in atherosclerosis and coronary plaque characteristics using enhanced AI quantification (RACE-AI)

Iskander B, Punnanithinont N, Kambalapalli S, Ichikawa K, Kinninger A, Krishnan S, Lakshmanan S, Roy S, Budoff M. Racial differences in atherosclerosis and coronary plaque[...]