Clonally expanded, thyrotoxic effector CD8+ T cells driven by IL-21 contribute to checkpoint inhibitor thyroiditis

By sjmartinez • May 19, 2023

Lechner MG, Zhou Z, Hoang AT, Huang N, Ortega J, Scott LN, Chen HC, Patel AY, Yakhshi-Tafti R, Kim K, Hugo W, Famini P, Drakaki A, Ribas A, Angell TE, Su MA. Clonally expanded, thyrotoxic effector CD8⁺ T cells driven by IL-21 contribute to checkpoint inhibitor thyroiditis. Sci Transl Med. 2023 May 17;15(696):eadg0675. doi: 10.1126/scitranslmed.adg0675. Epub 2023 May 17. PMID: 37196065.

Tags: Dermatology, Endocrinology, Hematology/Oncology, Publications

Why I’m Still Practicing

Bennett RG. Why I'm Still Practicing. Dermatol Clin. 2023 Oct;41(4):679-682. doi: 10.1016/j.det.2023.05.001. Epub 2023 Jul 3. PMID: 37718027.

Ipilimumab with or without nivolumab in PD-1 or PD-L1 blockade refractory metastatic melanoma: a randomized phase 2 trial

VanderWalde A, Bellasea SL, Kendra KL, Khushalani NI, Campbell KM, Scumpia PO, Kuklinski LF, Collichio F, Sosman JA, Ikeguchi A, Victor AI, Truong TG, Chmielowski ...

Year 2. September 18. Building Leaders One Student at a Time.

I am constantly amazed by the reach and impact of our faculty in mentoring and training graduates in our residency programs, pre-college students and undergraduates. ...