Reduced methionine synthase expression results in uracil accumulation in mitochondrial DNA and impaired oxidative capacity

By sjmartinez • April 20, 2023

Heyden KE, Fiddler JL, Xiu Y, Malysheva OV, Handzlik MK, Phinney WN, Stiles L, Stabler SP, Metallo CM, Caudill MA, Field MS. Reduced methionine synthase expression results in uracil accumulation in mitochondrial DNA and impaired oxidative capacity. PNAS Nexus. 2023 Mar 27;2(4):pgad105. doi: 10.1093/pnasnexus/pgad105. PMID: 37077889; PMCID: PMC10109189.

Tags: DNA, Endocrinology, folate, methionine synthase, Publications, uracil, vitamin B12

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