Translation of cytoplasmic UBA1 contributes to VEXAS syndrome pathogenesis

By sjmartinez • October 4, 2022

Ferrada MA, Savic S, Cardona DO, Collins JC, Alessi H, Gutierrez-Rodrigues F, Kumar DBU, Wilson L, Goodspeed W, Topilow JS, Paik JJ, Poulter JA, Kermani TA, Koster MJ, Warrington KJ, Cargo C, Tattersall RS, Duncan CJA, Cantor A, Hoffmann P, Payne EM, Bonnekoh H, Krause K, Cowen EW, Calvo KR, Patel BA, Ombrello AK, Kastner DL, Young NS, Werner A, Grayson PC, Beck DB. Translation of cytoplasmic UBA1 contributes to VEXAS syndrome pathogenesis. Blood. 2022 Sep 29;140(13):1496-1506. doi: 10.1182/blood.2022016985. PMID: 35793467.

Tags: Rheumatology

Efficacy of Intravenous Immunoglobulin for Systemic Manifestations of Dermatomyositis Beyond Muscular and Cutaneous: Sub-analysis of the ProDERM Study

Aggarwal R, Schessl J, Bata-Csörgő Z, Dimachkie MM, Griger Z, Moiseev S, Oddis CV, Schiopu E, Vencovský J, Clodi E, Levine T, Charles-Schoeman C; ProDERM[...]

Response to “Concerns Regarding PTX-3 Specificity and ROC Interpretation in the Study on Endothelial Biomarkers of SSc-Associated Pulmonary Hypertension”

Lammi M, Kolstad KD, Saketkoo LA, Khatri A, Utz PJ, Steen V, Chung L. Response to "Concerns Regarding PTX-3 Specificity and ROC Interpretation in the[...]

Tumor Necrosis Factor-Alpha Inhibitor-Induced Sarcoid-Like Reaction in a Patient With Juvenile Idiopathic Arthritis: A Case Report

Aung T, Prasanpanich M, Kaplan A, Eblen K, Fishbein GA. Tumor Necrosis Factor-Alpha Inhibitor-Induced Sarcoid-Like Reaction in a Patient With Juvenile Idiopathic Arthritis: A Case[...]