Single-cell RNA-seq of a soft-tissue sarcoma model reveals the critical role of tumor-expressed MIF in shaping macrophage heterogeneity

By rosaguerrero • June 23, 2022

Tessaro FHG, Ko EY, De Simone M, Piras R, Broz MT, Goodridge HS, Balzer B, Shiao SL, Guarnerio J. Single-cell RNA-seq of a soft-tissue sarcoma model reveals the critical role of tumor-expressed MIF in shaping macrophage heterogeneity. Cell Rep. 2022 Jun 21;39(12):110977. doi: 10.1016/j.celrep.2022.110977. PMID: 35732118; PMCID: PMC9249098.

Tags: Cancer, CP, Hematology/Oncology, macrophage migration inhibitory factor, MIF, Publications, sarcoma mouse models, soft tissue sarcoma, tumor inflammation, tumor microenvironment, tumor-associated macrophages, undifferentiated pleiomorphic sarcoma, UPS

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