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TRPV1

Canoe full of hot paddlers: TRPV1 neurons steering cardiorespiratory control

Wilson RJA, Jendzjowsky N. Canoe full of hot paddlers: TRPV1 neurons steering cardiorespiratory control. J Physiol. 2025 Oct 30. doi: 10.1113/JP290195. Epub ahead of print.[...]

By afschroeder • October 31, 2025
An Overview of the Effects of Tenapanor on Visceral Hypersensitivity in the Treatment of Irritable Bowel Syndrome with Constipation

Singh P, Sayuk GS, Rosenbaum DP, Edelstein S, Kozuka K, Chang L. An Overview of the Effects of Tenapanor on Visceral Hypersensitivity in the Treatment[...]

By sjmartinez • April 15, 2024
NHE3 inhibitor tenapanor maintains intestinal barrier function, decreases visceral hypersensitivity, and attenuates TRPV1 signaling in colonic sensory neurons

King AJ, Chang L, Li Q, Liu L, Zhu Y, Pasricha PJ, Wang J, Siegel M, Caldwell JS, Edelstein S, Rosenbaum DP, Kozuka K. NHE3[...]

By sjmartinez • January 23, 2024