Evaluation of Anti-HIV-1 HSPC-Based Gene Therapy with Negative Selection Marker in Pigtail Macaques

By afschroeder • October 28, 2026

Zhang J, Murray J, Mu W, Venugopal S, Yim E, Einhaus T, Radtke S, Peterson CW, Kiem HP, An DS. Evaluation of Anti-HIV-1 HSPC-Based Gene Therapy with Negative Selection Marker in Pigtail Macaques. Viruses. 2026 Oct 13;18(10):1133. doi: 10.3390/v18101133. PMID: 42944053; PMCID: PMC13709364.

Tags: C46 fusion inhibitor, CCR5 shRNA, Cetuximab, chimeric antigen receptor (CAR), Hematology/Oncology, hematopoietic stem and progenitor cell (HSPC) gene thCherapy; huEGFRt, HIV-1, lentiviral vector, non-human primate (NHP), Publications, SHIV

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