Strand-Resolved Mapping of siRNA Trafficking in Cells by Nanoscale Secondary Ion Mass Spectrometry

By afschroeder • October 24, 2026

Chen K, Nikan M, Li X, Hu S, Migawa MT, Guo J, Guagliardo P, Iyer KS, Bennett CF, Seth PP, Young SG, Jiang H. Strand-Resolved Mapping of siRNA Trafficking in Cells by Nanoscale Secondary Ion Mass Spectrometry. ACS Nano. 2026 Oct 6;20(39):26530-26540. doi: 10.1021/acsnano.6c08783. PMID: 42915640.

Tags: Cardiology/Epi, endolysosomes, high-resolution, NanoSIMS, nucleic acid therapeutics, oligonucleotides, Publications, siRNA

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