Identification of a spatially organized TREM2-associated permissive macrophage niche in human pulmonary tuberculosis alveolar pneumonia

Teles RMB, Benabdessalem C, Perrie J, Wei C, West J, de Andrade Silva BJ, Andrade PR, Mansky LA, Divaka P, Fischbacher L, Lam K, Ma F, Gu Y, Rategh K, Brown M, Pillai A, Lumamba K, Naidoo T, French SM, Romdhane E, Barbouche MR, Klechevsky E, Colonna M, Steyn AJC, Bensinger SJ, Barber DL, Rammeh S, Dulai PS, Bryson BD, Pellegrini M, Belisle JT, Bloom BR, Modlin RL. Identification of a spatially organized TREM2-associated permissive macrophage niche in human pulmonary tuberculosis alveolar pneumonia. Nat Commun. 2026 Aug 21;17(1):10817. doi: 10.1038/s41467-026-76814-8. PMID: 42875426; PMCID: PMC13669344.


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