Combined elevated C-reactive protein and detectable plasma RNA has predictive value for hospitalization during an outpatient COVID-19 convalescent plasma clinical trial

By afschroeder • October 16, 2026

Fukuta Y, Singh A, Ou J, Montalvo L, Di Germanio C, Huaman MA, Shenoy AG, Mosnaim GS, Patel B, Heath SL, Levine AC, Meisenberg BR, Anjan S, Blair JE, Currier JS, Paxton JH, Gerber J, Hammitt LL, Sutcliffe CG, Rausch W, Broderick PB, Cordisco ME, Greenblatt B, Cluzet VC, Cruser D, Oei K, Matthew A, Forthal DN, Zand MS, Kassaye SG, Cachay ER, Raval JS, Gniadek TJ, Spivak E, Gebo KA, Shoham S, Casadevall A, McBee NA, Shade DM, Ehrardt S, Layendecker O, Klein SL, Bloch EM, Tobian AAR, Ford D, Lane K, Hanley DF, Pekosz A, Lau B, Norris PJ, Sullivan DJ; CSSC (COVID 19 Serologic Studies Consortium) group. Combined elevated C-reactive protein and detectable plasma RNA has predictive value for hospitalization during an outpatient COVID-19 convalescent plasma clinical trial. J Clin Virol Plus. 2026 Nov;6(4):100268. doi: 10.1016/j.jcvp.2026.100268. Epub 2026 Sep 9. PMID: 42877651; PMCID: PMC13663306.

Tags: biomarkers, C-reactive protein, COVID-19 convalescent plasma, Hospitalization, Infectious Diseases, plasma RNA, Publications, SARS-CoV-2, viremia

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