Conceptual framework for the definition of disease modification in systemic sclerosis and potential implications for drug development and clinical study design

By afschroeder • September 15, 2026

Distler JHW, Assassi S, Gabrielli A, Allanore Y, Chung L, Cutolo M, Galdo FD, De Vries-Bouwstra JK, Domsic RT, Elhai M, Frech T, Hinchcliff M, Homey B, Khanna D, Krieg T, Kuwana M, Lescoat A, Low AHL, Matucci-Cerinic M, McMahan ZH, Molitor JA, Mouthon L, Nikpour M, Riemekasten G, Spierings J, Truchetet ME, Smith V, Varga J, Volkmann E, Vonk MC, Wang J, Xu D, Zhu H, Hoffmann-Vold AM, Denton CP, Distler O. Conceptual framework for the definition of disease modification in systemic sclerosis and potential implications for drug development and clinical study design. Ann Rheum Dis. 2026 Sep 14:S0003-4967(26)00491-7. doi: 10.1016/j.ard.2026.08.006. Epub ahead of print. PMID: 42736088.

Tags: Publications, Rheumatology

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