Casdatifan shows durable response linked to HIF-2α biology in kidney cancer

Choueiri TK, Merchan J, Patnaik A, Drakaki A, Rini BI, Rha SY, Lee JL, Ornstein MC, Kumar R, Hwang C, Shao Y, Park SH, Barata PC, McGregor BA, Foster P, Chen J, Eisen M, Cole H, Weeder B, Guan Y, Singh J, Kaplan A, Cho S, Markus R, Kabbarah O, McKay RR. Casdatifan shows durable response linked to HIF-2α biology in kidney cancer. Nature. 2026 Jul 1. doi: 10.1038/s41586-026-10718-x. Epub ahead of print. PMID: 42386974.


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