Evaluating datopotamab deruxtecan (Dato-DXd) as a novel treatment option for EGFR-mutated non-small cell lung cancer

By afschroeder • June 25, 2026

Tsvetkova O, Gil TE, Kassir G, Castanon S, Kollapaneni SS, Han A, Park SJ, Li R, Velez MA, Lisberg AE. Evaluating datopotamab deruxtecan (Dato-DXd) as a novel treatment option for EGFR-mutated non-small cell lung cancer. Future Oncol. 2026 Jun 25:1-16. doi: 10.1080/14796694.2026.2685854. Epub ahead of print. PMID: 42345080.

Tags: antibody-drug conjugates (ADC), datopotamab deruxtecan (Dato-DXd), DGSOM Student, EGFR-mutated non-small cell lung cancer, Fellow, General Internal Medicine, Hematology/Oncology, interstitial lung disease (ILD), osimertinib resistance, Publications, treatment sequencing, TROP2, TROPION-Lung trials

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