p21+TREM2+ senescent macrophages fuel inflammaging and metabolic dysfunction-associated steatotic liver disease

By afschroeder • April 17, 2026

Salladay-Perez IA, Avila I, Estrada L, Alexandru AC, Ponce C, Dhingra A, Torres G, Deng CY, Hegde R, Gensheimer J, Kale A, Heckenbach I, Hui S, Edillor C, Soto JA, Napior AJ, Little I, Larsen M, Rose J, Farahi L, Lopez Gonzalez EDJ, Krieger MR, Chowdhury K, Sharma M, Jiang Y, Williams K, Scheibye-Knudsen M, Koehler CM, Meyer JG, Mack JJ, Brenner C, Bensinger SJ, Lagger C, de Magalhães JP, Schilling B, Singh R, Verdin E, Lusis AJ, Covarrubias AJ. p21⁺TREM2⁺ senescent macrophages fuel inflammaging and metabolic dysfunction-associated steatotic liver disease. Nat Aging. 2026 Apr 16. doi: 10.1038/s43587-026-01101-6. Epub ahead of print. PMID: 41991686.

Tags: Cardiology/Epi, Digestive Diseases, Post Doc, Publications

Related Posts

Intensive Versus Standard Blood Pressure Control After Endovascular Thrombectomy in Acute Ischemic Stroke: A Meta-Analysis of Randomized Controlled Trials

Hashmi TM, Ahmed M, Ashraf H, Shakir M, Bhatti IA, Ahmed F, Alareed A, Hasan A, Ahmed R, Rafiq S, Aized MT, Fonarow GC, Hassan[...]

InChagas: Feasibility Study of a Tele-Education Strategy to Promote Early Identification and Care of People Living with Chagas Cardiomyopathy in an Endemic Community in Argentina

Gulayin PE, Gimenez C, Chirino D, Nascimento B, Salvá L, Cavallo AS, Gutierrez L, Blanco L, Flores LPC, Espina E, Shakil SS, Vervoort D, Davis[...]

Authors’ Perspective-Summary of the International Society for Heart and Lung Transplantation (ISHLT) Consensus Conference on Graft Dysfunction within the First 72 hours after Heart Transplantation: A 10-year Update

Kobashigawa J, Zuckermann A, Potena L, Ardehali A, Berman M, Chang PP, Esmailian F, Farr M, Hall S, Hsich E, Khush K, Kittleson M, Leprince[...]