A meta-analysis of smoking and fracture risk to update the FRAX® tool

By afschroeder • March 5, 2026

Schini M, Johansson H, Harvey NC, Lorentzon M, Liu E, Vandenput L, Leslie WD, Åkesson KE, Anderson FA, Azagra-Ledesma R, Bager CL, Beaudart C, Bischoff-Ferrari HA, Biver E, Bruyère O, Cauley JA, Center JR, Chapurlat R, Christiansen C, Cooper C, Crandall CJ, Cummings SR, da Silva JAP, Dawson-Hughes B, Diez-Perez A, Dufour AB, Eisman JA, Elders PJM, Ferrari S, Fujita Y, Fujiwara S, Glüer CC, Goldshtein I, Goltzman D, Gudnason V, Hall J, Hans D, Hoff M, Hollick RJ, Huisman M, Iki M, Ish-Shalom S, Jones G, Karlsson MK, Khosla S, Kiel DP, Koh WP, Koromani F, Kotowicz MA, Kröger H, Kwok T, Lamy O, Langhammer A, Larijani B, Lippuner K, McGuigan FEA, Mellström D, Merlijn T, Nguyen TV, Nordström A, Nordström P, Obermayer-Pietsch B, Ohlsson C, O'Neill TW, Orwoll ES, Pasco JA, Rivadeneira F, Schei B, Schott AM, Shiroma EJ, Siggeirsdottir K, Simonsick EM, Sornay-Rendu E, Sund R, Swart KM, Szulc P, Tamaki J, Torgerson DJ, van Schoor NM, van Staa TP, Vila J, Wareham NJ, Wright NC, Yoshimura N, Zillikens M, Zwart M, Kanis JA, McCloskey EV. A meta-analysis of smoking and fracture risk to update the FRAX® tool. Osteoporos Int. 2026 Mar 4. doi: 10.1007/s00198-026-07853-6. Epub ahead of print. PMID: 41779026.

Tags: Bone mineral density, Epidemiology, fracture, FRAX, General Internal Medicine, Osteoporosis, Publications, smoking

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