High concentrations of L-lysine cause mitochondrial damage and necrosis in isolated pancreatic acinar cells

By afschroeder • December 4, 2025

Végh ET, Balla Z, Dágó Á, Salamah O, Tóth B, Elperin J, Speakman S, Shalbueva N, Pallagi P, Rázga Z, Kiss L, Gukovskaya A, Rakonczay Z Jr. High concentrations of L-lysine cause mitochondrial damage and necrosis in isolated pancreatic acinar cells. Sci Rep. 2025 Dec 3. doi: 10.1038/s41598-025-29890-7. Epub ahead of print. PMID: 41339464.

Tags: acute pancreatitis, Basic amino acids, Digestive Diseases, l-arginine, L-lysine, L-ornithine, Pancreatic acinar cells, Publications, Veterans Administration

Dietary Therapies for Gastrointestinal Disorders

Limketkai BN, Shin A, Manitius N, Rau S, Smith J, Shah ND. Dietary Therapies for Gastrointestinal Disorders. Nutrients. 2026 Jun 1;18(11):1787. doi: 10.3390/nu18111787. PMID: 42280430.

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