High concentrations of L-lysine cause mitochondrial damage and necrosis in isolated pancreatic acinar cells

By afschroeder • December 4, 2025

Végh ET, Balla Z, Dágó Á, Salamah O, Tóth B, Elperin J, Speakman S, Shalbueva N, Pallagi P, Rázga Z, Kiss L, Gukovskaya A, Rakonczay Z Jr. High concentrations of L-lysine cause mitochondrial damage and necrosis in isolated pancreatic acinar cells. Sci Rep. 2025 Dec 3. doi: 10.1038/s41598-025-29890-7. Epub ahead of print. PMID: 41339464.

Tags: acute pancreatitis, Basic amino acids, Digestive Diseases, l-arginine, L-lysine, L-ornithine, Pancreatic acinar cells, Publications, Veterans Administration

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