Developing a Multilevel Polypill Implementation Bundle for Patients With Heart Failure With Reduced Ejection Fraction

By afschroeder • October 10, 2025

Chen JC, DeJong C, Agarwal M, Hairston AM, Durstenfeld MS, Powell B, McKay V, Huffman MD, Hsue PY, Agarwal A. Developing a Multilevel Polypill Implementation Bundle for Patients With Heart Failure With Reduced Ejection Fraction. JACC Adv. 2025 Oct 8:102195. doi: 10.1016/j.jacadv.2025.102195. Epub ahead of print. PMID: 41065619.

Tags: Cardiology/Epi, fixed-dose combination pill, Heart failure with reduced ejection fraction, implementation mapping, implementation science, polypill, Publications

Immune-instructive biomaterials in oral tissue regeneration and therapy

Park S, Linsley CS, Zarubova J, Wu BM, Li S. Immune-instructive biomaterials in oral tissue regeneration and therapy. Biomaterials. 2026 Apr 24;334:124232. doi: 10.1016/j.biomaterials.2026.124232. Epub[...]

Maternal hyperglycemia disrupts cardiomyocyte maturation via aberrant nucleotide metabolism and suppression of AMPK signaling

Nakano H, Kawahira N, Vesprey A, Nakano A. Maternal hyperglycemia disrupts cardiomyocyte maturation via aberrant nucleotide metabolism and suppression of AMPK signaling. Cell Rep. 2026[...]

Variation in Vasoactive Treatment Selection for Cardiogenic Shock: Insights From the Critical Care Cardiology Trials Network (CCCTN)

Hamilton DE, Shriver JL, Patel SM, Park JG, Michos ZE, Mathis MR, Adie SK, Alviar CL, Barnett CF, Berg DD, Bennett CE, Bohula EA, Carnicelli[...]