Role of CNNM4 in the progression of cholangiocarcinoma: implications for ferroptosis and therapeutic potential

By afschroeder • August 6, 2025

Mercado-Gómez M, Goikoetxea-Usandizaga N, Giné AE, Merlos Rodrigo MA, Afonso MB, Azkargorta M, Zapata-Pavas LE, Rejano-Gordillo CM, Romero MR, Mendizabal I, Rodrigues PM, Wu H, Rodríguez-Agudo R, Serrano-Maciá M, Olaizola P, Barrenechea-Barrenechea JA, González Recio I, G Fernandez-Barrena M, Overi D, Gaudio E, Schaeper U, Garcia-Longarte S, Yáñez-Bartolomé M, Peña-SanFelix P, Gil-Pitarch C, Lapitz A, Michalkova H, Heger Z, Conter C, Macias RIR, Carracedo A, Bañales J, Moreno V, Lamarca A, Singh R, Delgado TC, Martínez-Cruz LA, Elortza F, Avila MA, Martín C, Tian TV, Macarulla T, Buccella D, Cubero FJ, Calvisi DF, Carpino G, Marin JJG, Rodrigues CMP, Martinez-Chantar ML. Role of CNNM4 in the progression of cholangiocarcinoma: implications for ferroptosis and therapeutic potential. Gut. 2025 Aug 5:gutjnl-2024-333255. doi: 10.1136/gutjnl-2024-333255. Epub ahead of print. PMID: 40764063.

Tags: Cholangiocarcinoma, Digestive Diseases, Gene therapy, iron metabolism, Publications, reactive oxygen species

COVID-19 Pandemic-Related Disruptions in Routine Cirrhosis Care and Associated Clinical Outcomes among San Francisco Bay Area Veterans

Rubin JB, Loeb R, Monto A, Wong RJ, Cheung R, Batki SL, Ostacher MJ, Shen H, Hoggatt KJ, Satre DD, Khalili M. COVID-19 Pandemic-Related Disruptions[...]

Diesel exhaust induces gut microbiome dysbiosis and reduced fecal acetate: Role of acetate supplementation

Gupta R, Chang C, Vergnes L, Sulaiman D, Yin F, Stewart JA, Mehrabian M, Kaufman JD, Jacobs JP, Lusis AJ, Reue K, Rosenfeld ME, Araujo[...]

Earlier initiation of tenofovir in pregnancy with infant hepatitis B vaccination obviates the need for hepatitis B immune globulin

Pak K, Saab S. Earlier initiation of tenofovir in pregnancy with infant hepatitis B vaccination obviates the need for hepatitis B immune globulin. Transl Gastroenterol[...]