The accumulation of progerin underlies the loss of aortic smooth muscle cells in Hutchinson-Gilford progeria syndrome

By afschroeder • July 25, 2025

Kim PH, Kim JR, Heizer PJ, Jung H, Tu Y, Presnell A, Scheithauer J, Yu RG, Young SG, Fong LG. The accumulation of progerin underlies the loss of aortic smooth muscle cells in Hutchinson-Gilford progeria syndrome. Cell Death Dis. 2025 Jul 24;16(1):557. doi: 10.1038/s41419-025-07853-0. PMID: 40707465.

Tags: Cardiology/Epi, Publications

A deep learning phenome wide association study of the electrocardiogram

Hughes JW, Theurer J, Vukadinovic M, Rogers AJ, Somani S, Kang G, Ghazizadeh Z, O'Sullivan JW, Jain SS, Gomes B, Salerno M, Ashley E, Zou[...]

Novel insights into post-myocardial infarction cardiac remodeling through algorithmic detection of cell-type composition shifts

Gural B, Kirkland L, Hockett A, Sandroni P, Zhang J, Rosa-Garrido M, Swift SK, Chapski DJ, Flinn MA, O'Meara CC, Vondriska TM, Patterson M, Jensen[...]

Associations between Advanced Paternal Age and Adverse Reproductive Outcomes in the Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-Be (nuMoM2b)

Newman RA, Conley P, Esakoff T, Grobman W, Haas D, Wapner R, Chung J, Saade G, Bello NA. Associations between Advanced Paternal Age and Adverse[...]