Real-World Effectiveness and Safety of Evinacumab in Children and Adults With Homozygous Familial Hypercholesterolemia: A Multisite US Perspective

By sjmartinez • May 29, 2025

Wilkinson MJ, Bijlani P, Davidson MH, Duell PB, Horan M, Malloy MJ, Newfield RS, Pradeep P, Shah PK, Stock EO, Warden BA, Ito MK. Real-World Effectiveness and Safety of Evinacumab in Children and Adults With Homozygous Familial Hypercholesterolemia: A Multisite US Perspective. Arterioscler Thromb Vasc Biol. 2025 May 29. doi: 10.1161/ATVBAHA.124.322364. Epub ahead of print. PMID: 40438928.

Tags: Cardiology/Epi, Cedars Sinai DoM, Cholesterol, evinacumab, follow-up studies, Lipoproteins, Publications, retrospective studies

Mitochondrial dysfunction: the hidden catalyst in chronic kidney disease progression

Chen J, Zhou Q, Su L, Ni L. Mitochondrial dysfunction: the hidden catalyst in chronic kidney disease progression. Ren Fail. 2025 Dec;47(1):2506812. doi: 10.1080/0886022X.2025.2506812. Epub[...]

Established and Emerging Fluorine-18-Labeled Cardiac PET Radiotracers

Packard RRS, Pelletier-Galarneau M, Malhotra S, Dorbala S, Chen W, Dilsizian V. Established and Emerging Fluorine-18-Labeled Cardiac PET Radiotracers. JACC Cardiovasc Imaging. 2025 May 13:S1936-878X(25)00173-1.[...]

Structural mechanisms of PIP2 activation and SEA0400 inhibition in human cardiac sodium-calcium exchanger NCX1

Xue J, Zeng W, John S, Attiq N, Ottolia M, Jiang Y. Structural mechanisms of PIP2activation and SEA0400 inhibition in human cardiac sodium-calcium exchanger NCX1.[...]